Hewlett Packard Enterprise (HPE) has unveiled its latest advancements in the realm of artificial intelligence (AI) with the introduction of new NVIDIA GPUs. This move is aimed at catering to the growing demands for AI capabilities within enterprise data centers. The new HPE ProLiant Compute servers will be equipped with NVIDIA RTX PRO 6000 Blackwell Server Edition GPUs, housed in a 2U form factor to meet the increasing AI requirements of businesses.
These servers are designed to support a variety of workloads, ranging from generative and agentic AI to applications in robotics, industrial automation, visual computing, and simulation. Notably, the Gen12 ProLiant Compute servers come with enhanced security features such as HPE Integrated Lights Out (iLO) 7 Silicon Root of Trust and a secure enclave, ensuring robust protection against potential threats and vulnerabilities.
Moreover, HPE emphasizes the significance of lifecycle automation through HPE Compute Ops Management, which promises to streamline server management processes, significantly reducing IT hours and minimizing downtime. These server enhancements are poised to address the escalating need for GPU-accelerated computing power, offering organizations the flexibility to innovate and enhance productivity, security, and operational efficiency.
On the horizon is the forthcoming generation of HPE Private Cloud AI, set to embrace the latest NVIDIA RTX PRO 6000 GPUs. This evolution will enable scalability across GPU generations, featuring air-gapped management and support for enterprise multi-tenancy. The collaboration between HPE and NVIDIA will introduce support for cutting-edge AI models like Nemotron and Cosmos Reason, along with NVIDIA’s Blueprint for Video Search and Summarization (VSS 2.4).
These developments are tailored to assist customers in building AI agents capable of analyzing vast amounts of video data to extract valuable insights. The ultimate goal is to equip enterprises with the infrastructure necessary to meet the surging demand for AI inferencing, accelerating the deployment of AI solutions while upholding data control and operational efficiency.
Cheri Williams, Senior Vice President and General Manager at HPE, underscores the commitment to empowering enterprises in the AI era through innovative solutions that cater to diverse AI applications. Justin Boitano, Vice President of Enterprise AI at NVIDIA, highlights the importance of flexible and efficient infrastructure to support modern AI demands, emphasizing the accelerated performance achievable with NVIDIA RTX PRO 6000 Blackwell GPUs in HPE’s ProLiant servers.
The HPE ProLiant DL385 Gen11 and HPE ProLiant Compute DL380a Gen12 servers featuring NVIDIA RTX PRO 6000 Blackwell Server Edition GPUs are now available for ordering, with shipping commencing globally in September 2025. The support for NVIDIA Nemotron models, Cosmos Reason, and NVIDIA VSS 2.4 Blueprint within HPE Private Cloud AI is slated for the latter part of 2025, offering enterprises a comprehensive suite of AI capabilities to navigate the evolving landscape of AI technologies.
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