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The first edition of this book was published by Chapman and Hall Ltd. in 1996. The first edition contained nine chapters and, for all except one chapter, the original chapter authors agreed to update their chapter. Comparing these chapters gives the reader an idea of the development over a time span of more than 10 years between the two editions. In the preparation of the second edition we decided to add more chapters reflecting some important fields with significant contributions to present day fishery research. These are the use of internet for searching of information (Chapter 2), and the present state and use of remote sensing (Chapter 5), ecosystem modeling (Chapter 8) and visualization of data (Chapter 10). This second edition provides a valuable sampling of contemporary applications. Scientists have an opportunity to evaluate the suitability of different computer technology applications to their particular research situation thereby taking advantage of the experience of others. The chapters that follow are the fruition of this idea. The history behind this book started in 1989 when we were asked by Dr. Vidar Wespestad (previously: Alaska Fisheries Science Center, Seattle, USA) to prepare and convene a session at the 1992 World Fishery Congress in Athens, Greece on computer applications in fisheries. We agreed that the idea was a good one and the computer session in 1992 turned out to be very successful.
Reviewing exhaustively the current state of the art of tissue engineering strategies for regenerating bones and joints through the use of biomaterials, growth factors and stem cells, along with an investigation of the interactions between biomaterials, bone cells, growth factors and added stem cells and how together skeletal tissues can be optimised, this book serves to highlight the importance of biomaterials composition, surface topography, architectural and mechanical properties in providing support for tissue regeneration.
Maximizing reader insights into the importance of the interplay of these attributes with bone cells (osteoblasts, osteocytes and osteoclasts) and cartilage cells (chondrocytes), this book also provides a detailed reference as to how key signalling pathways are activated. The contribution of growth factors to drive tissue regeneration and stem cell recruitment is discussed along with a review the potential and challenges of adult or embryonic mesenchymal stem cells to further enhance the formation of new bone and cartilage tissues.
This book serves to demonstrate the interconnectedness of biomaterials, bone/cartilage cells, growth factors and stem cells in determining the regenerative process and thus the clinical outcome.
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